Human seipin binds anionic phospholipids
Web21 mrt. 2024 · Seipin (BSCL2/SPG17) is a widely expressed protein with a central role in fat storage. It is involved in the biogenesis of lipid droplets (LDs), fat storage organelles that are present in virtually all cell types, as well as in the development of mature adipocytes, specialized fat storage cells [ 1, 2 ]. Web4 okt. 2024 · Search worldwide, life-sciences literature Search. Advanced Search Coronavirus articles and preprints Search examples:
Human seipin binds anionic phospholipids
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Web11 mrt. 2024 · Human SEIPIN binds anionic phospholipids. Dev Cell 47, 248.e244–256.e244. 10.1016/j.devcel.2024.09.010. Crossref. Google Scholar. Cite article Cite article. Cite article COPY CITATION OR. Download to reference manager. If you have citation software installed, you can download article citation data to the citation manager … WebHuman SEIPIN Binds Anionic Phospholipids.
Web13 nov. 2024 · This is due to the unique structure of LDs, featuring a core of neutral lipids (NLs), surrounded by a monolayer of phospholipids (PLs). As a consequence of this peculiar composition and organization, the mechanism of … Webstructure of human seipin, which has a β-sandwich fold that can bind anionic phospholipids including PA. Moreover, our results in vitro and in vivo demonstrate that seipin functions to inhibit the activity of glycerol-3-phosphate acyltransferases (GPATs) to control the level of PA in the ER. Collectively,
WebUNSW Sydney NSW 2052 Australia Telephone +61 2 93851000 Authorised by Deputy Vice-Chancellor (Research) UNSW CRICOS Provider Code: 00098G ABN: 57 195 873 179 Web22 okt. 2024 · SEIPIN forms an undecamer, and both full-length and its lumenal domain bind strongly to anionic phospholipids including PA. Our results suggest that SEIPIN forms …
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WebHuman SEIPIN Binds Anionic Phospholipids. by Renhong Yan, Hongwu Qian, Ivan Lukmantara, Mingming Gao, Ximing Du, Nieng Yan, Hongyuan Yang. Developmental … top jiu jitsu brandsWeb(2024). Structure of the human LAT1-4F2hc heteromeric amino acid transporter complex. Nature568, 127-130. (* indicates co-first authors) Renhong Yan*, Hongwu Qian*, Ivan Lukmantara, Mingming Gao,Ximing Du, Nieng Yan, Hongyuan Yang. (2024). Human SEIPIN Binds Anionic Phospholipids. Dev Cell47, 248-256 e244. (* indicates co-first … top job vacancy sri lankaWeb22 okt. 2024 · Seipin, encoded by the gene Bernadelli-Seip congenital lipodystrophy type 2 (BSCL2), is an integral membrane protein with short N- and C-terminal segments in the … top jiu jitsu podcastsWeb4 okt. 2024 · Both full-length SEIPIN and its lumenal domain can bind anionic phospholipids including phosphatidic acid. Our results suggest that SEIPIN forms a … top jira pluginsWeb(2024). Structure of the human LAT1-4F2hc heteromeric amino acid transporter complex. Nature 568, 127-130. (* indicates co-first authors) Renhong Yan *, Hongwu Qian*, Ivan Lukmantara, Mingming Gao,Ximing Du, Nieng Yan, Hongyuan Yang. (2024). Human SEIPIN Binds Anionic Phospholipids. Dev Cell47, 248-256 e244. (* indicates co-first … top jiu jitsu booksWeb21 okt. 2024 · Both full-length SEIPIN and its lumenal domain can bind anionic phospholipids including phosphatidic acid. Our results suggest that SEIPIN forms a scaffold that helps maintain phospholipid homeostasis and surface tension of the ER. Topics: Seipin (81%), BSCL2 (70%), Phospholipid homeostasis (53%) Citations PDF … top jigsaw puzzles brandsWeb(2024). Structure of the human LAT1-4F2hc heteromeric amino acid transporter complex. Nature 568, 127-130. (* indicates co-first authors) Renhong Yan *, Hongwu Qian*, Ivan Lukmantara, Mingming Gao,Ximing Du, Nieng Yan, Hongyuan Yang. (2024). Human SEIPIN Binds Anionic Phospholipids. Dev Cell47, 248-256 e244. (* indicates co-first … top jiu jitsu gi