WebLamotrigine (Lamictal) is an antiepileptic. It's not exactly clear how this medication works to manage seizures and treat bipolar disorder. For seizures, research suggests that lamotrigine (Lamictal) can block and prevent your brain from sending certain chemicals or signals that can overly excite your nerves. Webdecrease lamotrigine concentrations by approximately 40%. (7, 12.3) • Estrogen-containing oral contraceptives decrease lamotrigine concentrations by approximately 50%. (7, 12.3) • Protease inhibitors lopinavir/ritonavir and atazanavir/lopinavir decrease lamotrigine exposure by approximately 50% and 32%, respectively. (7, 12.3)
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Lamotrigine (Lamictal): Basics, Side Effects & Reviews - GoodRx
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