Lysosomal-associated membrane protein 1 (LAMP-1) also known as lysosome-associated membrane glycoprotein 1 and CD107a (Cluster of Differentiation 107a), is a protein that in humans is encoded by the LAMP1 gene. The human LAMP1 gene is located on the long arm (q) of chromosome 13 at region 3, … Skatīt vairāk Residing primarily across lysosomal membranes, these glycoproteins consist of a large, highly glycosylated end with N-linked carbon chains on the luminal side of the membrane, and a short C-terminal tail exposed to the Skatīt vairāk LAMP1 and LAMP2 glycoproteins comprise 50% of all lysosomal membrane proteins, and are thought to be responsible in part for maintaining lysosomal integrity, pH and catabolism. The expression of LAMP1 and LAMP2 glycoproteins are linked, as deficiencies in … Skatīt vairāk • Chang MH, Karageorgos LE, Meikle PJ (2003). "CD107a (LAMP-1) and CD107b (LAMP-2)". Journal of Biological Regulators and Homeostatic Agents. 16 (2): 147–51. Skatīt vairāk LAMP1 expression on the surface of tumor cells has been observed for a number of different cancer types, particularly in highly metastatic … Skatīt vairāk • Cluster of differentiation Skatīt vairāk • LAMP1+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH) • PDBe-KB provides an overview of all the structure information available in the PDB for Human Lysosome-associated membrane glycoprotein 1 Skatīt vairāk TīmeklisLAMP1 分子背景 Lysosomal-associated membrane protein 1 (LAMP1) is also known as CD107a (Cluster of Differentiation 107a). LAMP1 / CD107a belongs to the LAMP family. This glycoprotein provides selectins with carbohydrate ligands. It may also play a role in tumor cell metastasis.
LAMP1蛋白；溶酶体关联膜蛋白1 (LAMP1)重组蛋白
TīmeklisLAMP1/CD107a Protein, Human (HEK293, Fc) is a recombinant human CD107a expressed in HEK 293 cells with a C-Fc tag at the C-terminus. LAMP1/CD107a Protein can be used as a functional marker for the identification of natural killer cell activity [1] [2]. 研究背景. Lysosomal associated membrane protein 1 (LAMP1 or CD107a) is a … Tīmeklis蛋白定位 可以定位于细胞质，细胞骨架，内膜系统，脂质囊泡，自噬体膜。 LC3B-I主要位于细胞质中，LC3B-II主要位于自噬体膜上。 图二：LC3B ICC实验结果图，Anti-LC3B [EPR18709] – 自噬体 Marker ( ab192890 )。 Hela细胞+/-氯喹 (50μM, 24小时)。 绿色：LC3B，红色：Tubulin，蓝色：DAPI。 异构体 & 翻译后修饰 … direct flights to jackson hole from ny
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Tīmeklis2024. gada 6. janv. · Lysosomal-associated membrane protein 1 (LAMP1) mainly localizes to lysosomes and late endosomes. We herein investigated the intracellular … TīmeklisLAMP1 is a heavily glycosylated membrane protein which contains a putative signal peptide, 18 sites for N-linked glycosylation, a single membrane-spanning segment and a short (11 amino acid) cytosolic tail. The LAMP proteins are involved in lysosome biogenesis and are required for fusion of lysosomes with phagosomes. Tīmeklis2024. gada 3. sept. · Despite widespread distribution of LAMP1 and the heterogeneous nature of LAMP1-labeled compartments, LAMP1 is routinely used as a lysosomal … forward dns resolution